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Results 1 - 10 for HMG-CoA reductase pathway

Mevalonate pathway - Wikipedia, the free encyclopedia
The mevalonate pathway or HMG-CoA reductase pathway or mevalonate-dependent (MAD) route or isoprenoid pathway, is an important cellular metabolic pathway present in all higher ...
http://wiki.healthhaven.com/HMG-CoA_reductase_pathway
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HMG-CoA reductase - Wikipedia, the free encyclopedia
HMG-CoA reductase (or 3-hydroxy-3-methyl-glutaryl-CoA reductase or HMGR) is the rate-controlling enzyme (EC 1.1.1.88) of the mevalonate pathway, the metabolic pathway that produces ...
http://wiki.healthhaven.com/HMG-CoA_reductase
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Cholesterol Synthesis
HMG-CoA Reductase, the rate-determining step on the pathway for synthesis of cholesterol, is a major control point. Regulation relating to cellular uptake of cholesterol will be ...
http://www.rpi.edu/dept/bcbp/molbiochem/MBWeb/mb2/part1/cholesterol.htm
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HMG-CoA reductase: Information from Answers.com
HMG-CoA reductase is a polytopic, transmembrane protein that catalyzes a key step in the mevalonate pathway (MetaCyc mevalonate pathway), which is involved in the synthesis of ...
http://www.answers.com/topic/hmg-coa-reductase-1
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HMG-CoA reductase - definition of HMG-CoA reductase by the Free Online ...
HMG-CoA reductase - a liver enzyme that is responsible for producing ... HMG-CoA reductase inhibitors HMG-CoA reductase pathway HMG-CoA synthase HMG-CoA synthase deficiency
http://www.thefreedictionary.com/HMG-CoA+reductase
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The clinical use of HMG CoA-reductase inhibitors (statins) and the ...
L The clinical use of HMG CoA-reductase inhibitors (statins) and the associated depletion of the ... Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature 1990 Feb 1 ;343 ...
http://www.fda.gov/ohrms/dockets/dailys/02/May02/052902/02p-0244-cp00001-02-Exhibit_A-vol1.pdf
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HMG-CoA reductase inhibitors and the malignant cell: the statin family ...
The statin family of drugs target HMG-CoA reductase, the rate-limiting enzyme of the mevalonate pathway, and have been used successfully in the treatment of hypercholesterolemia ...
http://www.nature.com/leu/journal/v16/n4/full/2402476a.html
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Modulatory effects of HMG-CoA reductase inhibitors in diabetic ...
Modulatory effects of HMG-CoA reductase inhibitors in ... of intermediaries in the mevalonate pathway (Fig. 1). Mevalonate is synthesized from HMG-CoA by HMG-CoA reductase.
http://www.fasebj.org/cgi/content/full/18/7/805
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Lovastatin-mediated G1 arrest is through inhibition of the proteasome ...
Because HMG-CoA reductase is degraded through the proteasome pathway and mevalonate increases the activity of the proteasome (this study), it follows that addition of mevalonate ...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC22141/?tool=pubmed
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Inflammation, Immunity, and HMG-CoA Reductase Inhibitors: Statins as ...
Dimmeler S, Aicher A, Vasa M, et al. HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway.
http://circ.ahajournals.org/cgi/content/full/109/21_suppl_1/II-18
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