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Results 1 - 10 for PDC-E2 Antigen

Antimitochondrial Antibodies - Digestion and Digestive-Related ...
The PDC-E2 antigen is also referred to as M2, a term introduced to designate it as the second mitochondrial antigen discovered by researchers interested in PBC.
http://www.medicinenet.com/antimitochondrial_antibodies/article.htm
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Blood -- Differential epitope mapping of antibodies to PDC-E2 ...
Autoantibodies to PDC-E2 antigen have only been detected in patients with disease or in those who subsequently develop PBC. One exception has been a subgroup of patients with multiple ...
http://bloodjournal.hematologylibrary.org/cgi/content/abstract/109/5/2001
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Primary Biliary Cirrhosis – Complete medical information regarding ...
The PDC-E2 antigen is also referred to as M2, a term introduced to designate it as the second mitochondrial antigen discovered by researchers interested in PBC.
http://www.medicinenet.com/primary_biliary_cirrhosis/page4.htm
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Differential epitope mapping of antibodies to PDC-E2 in patients with ...
Autoantibodies to PDC-E2 antigen have only been detected in patients with disease or in those who subsequently develop PBC. One exception has been a subgroup of patients with ...
http://www.ncbi.nlm.nih.gov/pubmed/17068145
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Modern Pathology - Autoimmune liver disease: overlap and outliers
These antibodies directed to the PDC-E2 antigen, a component of the pyruvate dehydrogenase enzyme complex present on the inner mitochondrial membrane, are highly specific (96%) for ...
http://www.nature.com/modpathol/journal/v20/n1s/full/3800684a.html
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Tables
Antigen Amino Acid Sequence CD4 + T Cell Response* CD8 + T-cell epitope : PDC-E2 (ILD) 157-176: G E K L S E G D L L A E I E T D K A T I + PDC-E2 (OLD) 30-49
http://www.medscape.com/content/2002/00/44/27/442752/442752_tab.html
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Journal of Clinical Investigation -- Quantitative and functional ...
More importantly, the response is focused on PDC-E2, the major mitochondrial antigen, lending further weight to the argument that either native modified PDC-E2 and/or a mimeotope ...
http://www.jci.org/articles/view/14698
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NOD.c3c4 congenic mice develop autoimmune biliary disease that ...
The epitopes recognized by anti-PDC-E2 and au-toreactive CD4 + and CD8 + T cells map within the inner lipoyl domain of PDC-E2 (4-6). Intriguingly, the mitochondrial PDC-E2 auto-antigen is ...
http://jem.rupress.org/cgi/reprint/203/5/1209.pdf
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USCAP 2003 Annual Meeting
Antibodies directed to the PDC-E2 antigen, a component of the pyruvate dehydrogenase enzyme complex present on the inner mitochondrial membrane, are highly specific (96 ...
http://www.uscap.org/site~/92nd/shortbileh1.htm
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NOD.c3c4 congenic mice develop autoimmune biliary disease that ...
Immunoreactivity of serum samples to the major mitochondrial antigen, PDC-E2, was studied by immunoblotting as described previously . In brief, 20 µg recombinant protein was ...
http://jem.rupress.org/cgi/content/full/203/5/1209
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